Direct Aldimine Oxidative Reaction: A General Approach toward Amides

Abstract The first procedure to directly access amides from stable aldimine under potassium peroxymonosulfate (Oxone)/DMF system was reported. It involved a nucleophilic addition of imine with Oxone, a similar Baeyer‐Villiger rearrangement and a tautomerization process to afford amides in excellent yield. The present work opens up an efficient method to amides under mild conditions.