Co(OAc)2/TBHP as a Highly Active Catalytic System for the Selective Oxidation of Aromatic Amines to Nitro Derivatives

Abstract An efficient cobalt-catalyzed protocol for the selective oxidation of anilines using a combination of inexpensive tert-butyl hydroperoxide and Co(OAc)2·4H2O without any ligand has been developed, providing the nitroarene products in good to excellent yields (up to 96%).