转录因子
机制(生物学)
植物代谢
利用
计算生物学
基因表达调控
生物
基因
生物技术
生物化学
计算机科学
核糖核酸
哲学
计算机安全
认识论
作者
Min Shi,Zhang Siwei,Zizhen Zheng,Itay Maoz,Lei Zhang,Guoyin Kai
摘要
The basis of modern pharmacology is the human ability to exploit the production of specialized metabolites from medical plants, for example, terpenoids, alkaloids, and phenolic acids. However, in most cases, the availability of these valuable compounds is limited by cellular or organelle barriers or spatio-temporal accumulation patterns within different plant tissues. Transcription factors (TFs) regulate biosynthesis of these specialized metabolites by tightly controlling the expression of biosynthetic genes. Cutting-edge technologies and/or combining multiple strategies and approaches have been applied to elucidate the role of TFs. In this review, we focus on recent progress in the transcription regulation mechanism of representative high-value products and describe the transcriptional regulatory network, and future perspectives are discussed, which will help develop high-yield plant resources.
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