Carotid endarterectomy or stenting or best medical treatment alone for moderate-to-severe asymptomatic carotid artery stenosis: 5-year results of a multicentre, randomised controlled trial

医学颈动脉内膜切除术无症状的狭窄临床终点冲程（发动机）随机对照试验外科颈动脉支架置入术动脉内膜切除术内科学机械工程工程类

作者

Tilman Reiff,Hans‐Henning Eckstein,Ulrich Mansmann,Olav Jansen,Gustav Fraedrich,Harald Mudra,Dittmar Böckler,Michael Böhm,E. Sebastian Debus,Jens Fiehler,Klaus Mathias,E. Bernd Ringelstein,Jürg Schmidli,Robert Stingele,Ralf Zahn,Thomas Zeller,Wolf‐Dirk Niesen,Kristian Barlinn,Andreas Binder,Jörg Glahn,Werner Hacke,Peter A. Ringleb,Friedhelm Beyersdorf,Roland-Richard Macharzina,Gabriele Lechner,Carolin Menz,S Schonhardt,M Weinbeck,Olga Greb,Dagmar Otto,Thomas Winker,Hermann Berger,Holger Poppert,A. Kühnl,Volker Pütz,Kathrin Haase,Ulf Bodechtel,Norbert Weiss,Hendrik Bergert,Johannes Meyne,Justus Groß,Matthias Kruse,B Gerdes,Wolf‐Dieter Reinbold,Helge Wuttig,Andreas Maier-Hasselmann,Manuela Segerer,H. Fuchs,Sabine Gass,Christoph Groden,Marco Niedergethmann,Martin Griebe,Michael Rosenkranz,Jürgen Beck,Götz Thomalla,H. Zeumer,M. Jauß,W. Kneist,Martina Kneist,T Staudacher,Alfons Bernhard,Petra Jost,N Prey,J. Knippschild,O Kastrup,Martin Köhrmann,Benedikt Frank,V Bongers,Johannes Hoffmann,Horst-Wilhelm Kniemeyer,Michael Knauth,Kathrin Wasser,Tomislav Stojanović,H Emmert,Josef Tacke,Bernhard Schwalbe,Eunmi Nam,U van Lengerich,Stephan Lowens,Klaus Gröschel,Timo Uphaus,Sonja Gröschel,Stephan Boor,Bernhard Dorweiler,Elisabeth Schmid,Hans Henkes,T. Hupp,Oliver C. Singer,Gerhard F. Hamann,Michaela Wagner-Heck,Sibylle Kerth-Krick,Metin Kılıç,Peter Huppert,Kurt Niederkorn,J. Fruhwirth,Günther Klein,Ulrich Pulkowski,Karsten Jöster,Jens-Henning Wacks,E Kloppmann,Bijan Vatankhah,Silke Hopf-Jensen,Henning Stolze,Stefan Müller‐Hülsbeck,Knut Peer Walluscheck,Hans-Michael Schmitt,Albert Grüger,J. Seemann,B Tilahun,Martin Dichgans,Frank A. Wollenweber,A Dörr,A Zollver,Gábor Gäbel,G Hedtmann,Rainer Kollmar,Detlef Claus,C Petermann,Stefanie Kirsch,Branko Bosnjak,Johannes Heiß,Holger Mühling,Silke Wunderlich,Peter Nikolaus Sabisch,Georg Gahn,Martin Störck,Sebastian Arnold,Urs Fischer,Jan Gralla,Matthias von Mering,Rüdiger Dißmann,D. Kirsch,Christoph Schmidauer,Peter Waldenberger,Martin Furtner,H. Kazarians,Péter Breuer,Christian Arning,Jürgen Rieper,Georg Schmidt,Marcel Arnold,Gerhard Schroth,Jens Weise,Jürgen Zanow,Thomas E. Mayer,Rudolf Töpper,W. Groß-Fengels,H. Daum,Ralf Dittrich,Martin Ritter,Bernd Kasprzak,Giovanni Torsello,Carsten Pohlmann,Roland Brüning,Péter Breuer,Alexander Crispin,Miriam Hofmann,T. Müller,Erwin Blessing,Markus Möhlenbruch,I Ludwig,Hemasse Amiri

出处

期刊：Lancet Neurology [Elsevier]
日期：2022-09-14 卷期号：21 (10): 877-888 被引量：64

链接

nih.govdoi.org

标识

DOI：10.1016/s1474-4422(22)00290-3

摘要

The optimal treatment for patients with asymptomatic carotid artery stenosis is under debate. Since best medical treatment (BMT) has improved over time, the benefit of carotid endarterectomy (CEA) or carotid artery stenting (CAS) is unclear. Randomised data comparing the effect of CEA and CAS versus BMT alone are absent. We aimed to directly compare CEA plus BMT with CAS plus BMT and both with BMT only.

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Carotid endarterectomy or stenting or best medical treatment alone for moderate-to-severe asymptomatic carotid artery stenosis: 5-year results of a multicentre, randomised controlled trial

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