The pathogenesis of appendicitis in 2022: More than just a fecalith

Beliefs regarding the cause of acute appendicitis are commonly based on classic surgical teachings that suggest it occurs due to appendiceal luminal obstruction that is caused by fecaliths, lymphoid hyperplasia, infectious agents such as parasites, foreign bodies and tumors. This short communication presents a contemporary overview of the etiology of appendicitis based on current literature.