电泳沉积
材料科学
壳聚糖
生物相容性
Zeta电位
复合数
分散剂
表面电荷
聚合物
化学工程
涂层
纳米技术
复合材料
纳米颗粒
冶金
色散(光学)
化学
物理化学
工程类
物理
光学
作者
Egemen Avcu,Fatih Erdem Baştan,Hasan Zuhudi Abdullah,Muhammad Atiq Ur Rehman,Yasemin Yıldıran Avcu,Aldo R. Boccaccını
标识
DOI:10.1016/j.pmatsci.2019.01.001
摘要
Abstract Chitosan is one of the most widely used natural biopolymers for a great variety of biomedical applications owing to its biocompatibility, biodegradability, and antibacterial activity, being generally regarded as a safe material. It can be employed as a dispersant, binder, and surface charge agent for particles in suspension. Electrophoretic deposition (EPD) of chitosan, especially in combination with other materials, is receiving increasing attention for biomedical applications. This article presents a comprehensive review of the field of EPD of chitosan-based composite coatings by highlighting their microstructural, mechanical, surface, and biological properties. Since suspension characteristics have significant influences on the deposition mechanisms, kinetics, and on the overall properties of the electrophoretically deposited coatings, suspension parameters such as concentration, viscosity, and zeta potential are discussed, including chitosan-based suspensions with hydroxyapatite, bioactive glass particles, carbonaceous materials and other inorganic and organic materials. The deposition mechanisms proposed for each composite system are highlighted. Moreover, the effects of key EPD process parameters on the microstructural homogeneity, mechanical properties as well as surface and biological characteristics of the coatings are emphasised, and specific approaches for future research are proposed based on the state-of-the-art and considering EPD produced chitosan-based coatings in applications such as tissue engineering and drug delivery systems.
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