精神病理学
心理学
神经质
五大性格特征
人格
外向与内向
和蔼可亲
尽责
特质
旋回作用
发展心理学
临床心理学
神经科学
社会心理学
计算机科学
程序设计语言
大脑皮层
作者
Courtland S. Hyatt,Max M. Owens,Joshua C. Gray,NATHAN T CARTER,James MacKillop,Lawrence H. Sweet,Josh Miller
标识
DOI:10.31234/osf.io/he738
摘要
Although personality traits have been linked to internalizing and externalizing psychopathology, the extent to which these traits and psychopathological phenotypes share a common neuroanatomical structure is unclear. To address this gap, we used structural neuroimaging and self-report data from 1101 participants in the Human Connectome Project to generate neuroanatomical profiles (NAPs) of FFM traits and psychopathology indices composed of the thickness, surface area, and gray matter volume of each region in the Desikan atlas, then used a profile matching approach to compare the absolute similarity of the FFM trait NAPs and psychopathology index NAPs. These analyses indicated that the NAPs derived from Neuroticism and Extraversion demonstrated medium to large positive and negative absolute similarities to the NAPs of internalizing psychopathology, respectively. Similarly, the NAPs of Agreeableness and Conscientiousness showed medium to large negative relations with the NAPs of antisocial behavior and substance use, respectively. These results suggest that similar neuroanatomical correlates underlie specific personality traits and symptoms of psychopathology, providing support for dimensional models that incorporate personality traits into the etiology and manifestation of psychopathology.
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