Here we propose a framework for considering the justice issues of industrial cluster decarbonisation, a pressing challenge confronting many industrialised economies. Industrial clusters are large, multi-point source emitters, users of energy and employers of regional and national significance. In the UK, establishing low carbon industrial clusters is one of several grand challenges of industrial strategy. Theorising the just transition of industrial clusters requires concepts from multiple literatures. We abstract relevant themes from the intersections of the literatures of just transitions, innovation studies and sociotechnical transitions, and public participation in spatial planning, and illustrate their empirical relevance. The broad themes of our framework are (i) politics, space and institutions, with sub-themes of justice, democracy, financialization; (ii) new processes and procedures, with sub-themes of legal recognition of public concerns, community-based planning, community capacity enhancement and life cycle impact assessment; and (iii) correlates of acceptance and resistance, with sub-themes of environmental values, perceived loss of amenity, pre-existing politics, perceptions of just process and trust in the developer. The framework is intended to both guide the design of just transition processes ex-ante and evaluate these post-hoc.