硒
亚砷酸盐
砷
蜡样芽孢杆菌
氧化应激
细菌
类金属
DNA损伤
基因
化学
基因表达
生物
微生物学
生物化学
遗传学
DNA
金属
有机化学
作者
Soniya Dhanjal,Anil Kumar Singh,Swaranjit Singh Cameotra
标识
DOI:10.1080/01490451.2013.822613
摘要
AbstractIn our earlier study, a bacterial isolate, Bacillus cereus (strain CM100B) was reported to detoxify selenite oxyions with concomitant generation of amorphous selenium (Se0) nanospheres. A whole genome transcriptional analysis was performed to study the genome wide stress response of this bacterium to elevated concentrations of selenite and arsenite oxyions. Data analysis revealed that various genes related to metabolic pathways, transcription, DNA repair and replication and oxidative stress were activated symptomatic of the various stress related response. It seems that in order to cope with the oxidative stress that results from the exposure to oxidants such as selenite and arsenite, bacteria have evolved multiple, and often redundant, defense systems to eliminate the reactive oxyion species (ROS) from the cell.Keywords: arsenicBacillus sp.metal toxicityselenium FundingWe are thankful to the Council of Scientific and Industrial Research (CSIR), India for the financial support.
科研通智能强力驱动
Strongly Powered by AbleSci AI