医学
肠外营养
优势比
前瞻性队列研究
并发症
肠内给药
队列研究
风险因素
队列
内科学
临床营养学
医学营养疗法
混淆
外科
儿科
作者
Jie Bin,Jiang Zhu,Marie T. Nolan,David T. Efron,Shai Nan Zhu,Kang Yu,Jens Kondrup
出处
期刊:Nutrition
[Elsevier]
日期:2010-11-01
卷期号:26 (11-12): 1088-1093
被引量:105
标识
DOI:10.1016/j.nut.2009.08.027
摘要
To evaluate the impact of nutritional support on clinical outcomes in patients at nutritional risk defined by the Nutritional Risk Screening 2002.In this prospective cohort study, hospitalized patients from three departments in Johns Hopkins Hospital in Baltimore and two teaching hospitals in Beijing were recruited from March 2007 to May 2008. Data were collected on the nutritional risk screening, application of parenteral nutrition and enteral nutrition, surgery, complications, and length of stay.There were 1831 patients recruited, with 45.2% of them at nutritional risk. Of the "at-risk" patients, the complication rate was significantly lower in the nutritional-support group than in the no-support group (20.3% versus 28.1%, P = 0.009), mainly because of the lower rate of infectious complications (10.5% versus 18.9%, P < 0.001). Subgroup analysis showed the complication rate was significantly lower in the enteral nutrition group (P < 0.001) but not in the parenteral nutrition group (P = 0.29) when compared with the no-support group. Of the patients without nutritional risk, the complication rate was not different between the nutritional-support group and the no-support group (P = 0.10). Multivariate analysis showed nutritional support was a protective factor for complications in at-risk patients when adjusted for confounders (odds ratio 0.54, P < 0.001). No difference in length of stay was found.The findings suggested that nutritional support was beneficial to the patients at nutritional risk according to Nutritional Risk Screening 2002 by a lower complication rate.
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