Studies on the chemistry of O,N- and S,N-containing heterocycles.4. Investigations on the nucleophilic substitution of activated 1,5-benzothiazepines

Abstract The reaction of the activated 1,5‐benzothiazepine 1a with various amines is studied. In contrast to the phenylsubstituted derivative 1b no ring contraction but nucleophilic substitution is observed. Two novel ring systems 8 and 9 are obtained by nitrosation of 3g and by reaction of 1a with anthranilic acid, respectively.