Regioselective Cross‐Dehydrogenative Coupling of Chromones and Non‐Activated Arenes

Flavone from benzene: An efficient regiocontrolled CH functionalization of chromones at the C2 position is described. This method enables facile oxidative cross-coupling reactions with non-activated arenes by a palladium-catalyzed twofold CH functionalization. The substrate scope is broad and permits the construction of various flavone derivatives, which are privileged structures as well as prevalent motifs in many biologically active compounds. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.