Synthesis of an Anti ‐α‐Amino Epoxide by One‐Carbon Homologation of an α‐Amino Ester: (2 S ,3 S )‐1,2‐Epoxy‐3‐(Boc‐Amino)‐4‐Phenylbutane

Abstract Trimethylsulfoxonium iodide Boc‐L‐phenylalanine 4‐nitrophenyl ester Dimethylsulfoxonium ( S )‐2‐oxo‐3‐(Boc‐amino)‐4‐phenylbutylide ( S )‐1‐Chloro‐3‐(Boc‐amino)‐4‐phenyl‐2‐butanone Lithium tri‐tert‐butoxyaluminum hydride (2 S , 3 S )‐1,2‐Epoxy‐3‐(Boc‐amino‐4‐phenylbutane