Portable devices and mobile instruments for infectious diseases point-of-care testing

软件可移植性 检测点注意事项 注意事项 周转时间 计算机科学 移动设备 医疗保健 风险分析(工程) 医学 数据科学 万维网 病理 经济增长 操作系统 经济 程序设计语言
作者
Luc Bissonnette,Michel G. Bergeron
出处
期刊:Expert Review of Molecular Diagnostics [Informa]
卷期号:17 (5): 471-494 被引量:26
标识
DOI:10.1080/14737159.2017.1310619
摘要

Rapidity, simplicity, and portability are highly desirable characteristics of tests and devices designed for performing diagnostics at the point of care (POC), either near patients managed in healthcare facilities or to offer bioanalytical alternatives in external settings. By reducing the turnaround time of the diagnostic cycle, POC diagnostics can reduce the dissemination, morbidity, and mortality of infectious diseases and provide tools to control the global threat of antimicrobial resistance. Areas covered: A literature search of PubMed and Google Scholar, and extensive mining of specialized publications, Internet resources, and manufacturers' websites have been used to organize and write this overview of the challenges and requirements associated with the development of portable sample-to-answer diagnostics, and showcase relevant examples of handheld devices, portable instruments, and less mobile systems which may or could be operated at POC. Expert commentary: Rapid (<1 h) diagnostics can contribute to control infectious diseases and antimicrobial resistant pathogens. Portable devices or instruments enabling sample-to-answer bioanalysis can provide rapid, robust, and reproducible testing at the POC or close from it. Beyond testing, to realize some promises of personalized/precision medicine, it will be critical to connect instruments to healthcare data management systems, to efficiently link decentralized testing results to the electronic medical record of patients.

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