Neuroimaging Findings Related to Behavioral Disturbances in Alzheimer's Disease: A Systematic Review

Background: Behavioral and psychological symptoms of dementia (BPSD) associated with Alzheimer's Disease (AD) have been linked to structural and functional alterations in fronto-temporal circuits and cortical abnormalities. However, little is known on how specific volumetric and functional brain changes may be associated with the frequency, severity and pattern of BPSD. Keywords: Alzheimer's disease, behavior, BPSD, cognition, cortical, neuroimaging, psychological, symptoms, white matter.