Reversible Photoswitching of a G‐Quadruplex

Angewandte Chemie International EditionVolume 48, Issue 36 p. 6671-6674 Communication Reversible Photoswitching of a G-Quadruplex Shinzi Ogasawara Dr., Shinzi Ogasawara Dr. o_shinji@riken.jp Bioengineering Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan), Fax: (+81) 48-462-4658Search for more papers by this authorMizuo Maeda Prof. Dr., Mizuo Maeda Prof. Dr. Bioengineering Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan), Fax: (+81) 48-462-4658Search for more papers by this author Shinzi Ogasawara Dr., Shinzi Ogasawara Dr. o_shinji@riken.jp Bioengineering Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan), Fax: (+81) 48-462-4658Search for more papers by this authorMizuo Maeda Prof. Dr., Mizuo Maeda Prof. Dr. Bioengineering Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan), Fax: (+81) 48-462-4658Search for more papers by this author First published: 19 August 2009 https://doi.org/10.1002/anie.200902183Citations: 51Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Getting a grip: G-quadruplex formation can be regulated by reversible cis–trans photoisomerization of the photochromic nucleobase 8-fluorenylvinyl-2′-deoxyguanosine (see picture: fluorene red, guanine green). Switching between a very stable quadruplex state and a non-structured state allows controlled binding to thrombin (pink). Citing Literature Supporting Information Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Filename Description anie_200902183_sm_miscellaneous_information.pdf606.9 KB miscellaneous_information Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume48, Issue36August 24, 2009Pages 6671-6674 RelatedInformation