Aptasensors for mycotoxins in foods: Recent advances and future trends

适体 风险分析(工程) 真菌毒素 生化工程 计算机科学 适应性 人类健康 生物技术 纳米技术 工程类 生物 业务 材料科学 医学 环境卫生 遗传学 生态学
作者
Yujiao Hou,Boyu Jia,Ping Sheng,Xiaofang Liao,Linchun Shi,Ling Fang,Lidong Zhou,Weijun Kong
出处
期刊:Comprehensive Reviews in Food Science and Food Safety [Wiley]
卷期号:21 (2): 2032-2073 被引量:95
标识
DOI:10.1111/1541-4337.12858
摘要

Abstract Mycotoxin contamination in foods has posed serious threat to public health and raised worldwide concern. The development of simple, rapid, facile, and cost‐effective methods for mycotoxin detection is of urgent need. Aptamer‐based sensors, abbreviated as aptasensors, with excellent recognition capacity to a wide variety of mycotoxins have attracted ever‐increasing interest of researchers because of their simple fabrication, rapid response, high sensitivity, low cost, and easy adaptability for in situ measurement. The past few decades have witnessed the rapid advances of aptasensors for mycotoxin detection in foods. Therefore, this review first summarizes the reported aptamer sequences specific for mycotoxins. Then, the recent 5‐year advancements in various newly developed aptasensors, which, according to the signal output mode, are divided into electrochemical, optical and photoelectrochemical categories, for mycotoxin detection are comprehensively discussed. A special attention is taken on their strengths and limitations in real‐world application. Finally, the current challenges and future perspectives for developing novel highly reliable aptasensors for mycotoxin detection are highlighted, which is expected to provide powerful references for their thorough research and extended applications. Owing to their unique advantages, aptasensors display a fascinating prospect in food field for safety inspection and risk assessment.
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