Chlorination has been used in the fields of organic solar cells (OSCs) for a long time, and impressive progress has been made over the years. Recently developed chlorinated OSCs have achieved an efficiency of over 18%. For better understanding and application of chlorination in the fields of OSCs, we will briefly introduce the general properties of chlorine and recent advances in its introduction and applications in OSCs in this cluster article. Finally, we also provide a short discussion of current questions regarding chlorination in OSCs and future developments in this area.