Association of blood lipids with mortality in COVID‐19 patients

Abstract The aim of this study was to investigate the association between lipid levels and mortality in individuals hospitalized (ward/intensive care unit) for coronavirus disease 2019 (COVID‐19). This retrospective cohort study was conducted with COVID‐19 patients admitted to a public hospital between April 2020 and 2021. Age, sex, and chronic disease status of the participants were analyzed as general information. Information on biochemical tests (high‐density lipoprotein [HDL], low‐density lipoprotein [LDL], triglycerides, total cholesterol, c‐reactive protein [CRP]) and haemogram parameters were obtained from the hospital's automated system. The study sample consisted of 501 COVID‐19 patients aged 24–94 years. According to mortality status, total cholesterol, HDL, LDL, and lymphocyte levels were higher, while CRP, neutrophil, and white blood cell levels were lower in survivors ( p < 0.05). The risk of mortality was found to be higher with lower LDL and HDL cholesterol levels in COVID‐19 patients ( p < 0.05). The results of this study showed that alterations in lipoprotein metabolism are associated with mortality in COVID‐19 patients. Therefore, it is important to evaluate and monitor the blood lipid profile in COVID‐19 patients.