光热治疗
生物相容性
纳米技术
材料科学
纳米材料
生物膜
大肠杆菌
抗菌活性
细菌
抗菌剂
光热效应
化学
光敏剂
水消毒
致病菌
抗生素
金黄色葡萄球菌
灭菌(经济)
抗菌剂
微生物学
萘啶酸
组合化学
作者
Panyong Wang,Qiannan You,Yulu Liu,Huimin Miao,Wen‐Fei Dong,Li Li
标识
DOI:10.1016/j.colsurfb.2024.113874
摘要
The growing resistance of bacteria to antibiotics has posed challenges in treating associated bacterial infections, while the development of multi-model antibacterial strategies could efficient sterilization to prevent drug resistance. High-entropy MXene has emerged as a promising candidate for antibacterial synergy with inherent photothermal and photodynamic properties. Herein, a high-entropy nanomaterial of MXene/CDs was synthesized to amplify oxidative stress under near-infrared laser irradiation. Well-exfoliated MXene nanosheets have proven to show an excellent photothermal effect for sterilization. The incorporation of CDs could provide photo-generated electrons for MXene nanosheets to generate ROS, meanwhile reducing the recombination of electron-hole pairs to further accelerate the generation of photo-generated electrons. The MXene/CDs material demonstrates outstanding synergistic photothermal and photodynamic effects, possesses excellent biocompatibility and successfully eliminates drug-resistant bacteria as well as inhibits biofilm formation. While attaining a remarkable killing efficiency of up to 99.99% against drug-resistant Escherichia coli and Staphylococcus aureus, it also demonstrates outstanding antibacterial effects against four additional bacterial strains. This work not only establishes a synthesis precedent for preparing high-entropy MXene materials with CDs but also provides a potential approach for addressing the issue of drug-resistant bacterial infections.
科研通智能强力驱动
Strongly Powered by AbleSci AI