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An enhanced recovery programme significantly improves postoperative outcomes after surgical aortic valve replacement

医学 主动脉瓣置换术 围手术期 倾向得分匹配 重症监护室 心脏外科 狭窄 入射(几何) 射血分数 死亡率 内科学 外科 心力衰竭 心脏病学 物理 光学
作者
Albane Giger,Clément Schneider,Sandrine Marguerite,Dharmesh Ramlugun,Anne-Lise Maechel,Olivier Collange,Paul-Michel Mertès,Jean‐Philippe Mazzucotelli,Michel Kindo
出处
期刊:European Journal of Cardio-Thoracic Surgery [Oxford University Press]
卷期号:63 (5) 被引量:2
标识
DOI:10.1093/ejcts/ezad125
摘要

Abstract OBJECTIVES Evidence regarding the benefits of an enhanced recovery after cardiac surgery (ERACS) programme is lacking. The aim of this study was to analyse the impact of a systematic standardized ERACS programme for patients undergoing isolated elective surgical aortic valve replacement (SAVR) for aortic stenosis in terms of hospital mortality and morbidity, patient blood management and length of stay. METHODS Patients undergoing isolated elective SAVR for aortic stenosis between 2015 and 2020 were identified from our database (n = 941). The standardized systematic ERACS programme was implemented in November 2018. Propensity score matching indicated that 259 patients would receive standard perioperative care (control group) and 259 patients would receive the ERACS programme (ERACS group). The primary outcome was hospital mortality. The secondary outcomes were hospital morbidity, patient blood management and length of stay. RESULTS Both groups had similar hospital mortality rates (0.4%). The ERACS group had a significantly lower troponin I peak level (P < 0.001), a larger proportion of improved perioperative left ventricular ejection fractions (P = 0.001), a lower incidence of bronchopneumonia (P = 0.030), a larger proportion of patients with mechanical ventilation <6 h (P < 0.001), a lower incidence of delirium (P = 0.028) and less acute renal failure (P = 0.013). The ERACS group had a significantly lower rate of red blood cell transfusions (P = 0.002). The intensive care unit stay was significantly shorter in the ERACS group than in the control group (P = 0.039). CONCLUSIONS The standardized systematic ERACS programme significantly improved postoperative outcomes and should become the reference for the perioperative care pathway for patients undergoing SAVR.

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