Mortality in patients with septic cardiomyopathy identified by longitudinal strain by speckle tracking echocardiography: an updated systematic review and meta-analysis with trial sequential analysis

Septic cardiomyopathy is associated with poor outcomes but its definition remains unclear. In a previous meta-analysis, left ventricular (LV) longitudinal strain (LS) showed significant prognostic value in septic patients, but findings were not robust due to a limited number of studies, differences in effect size and no adjustment for confounders.