亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Cerebral Blood Flow Patterns in Patients With Low‐Flow Carotid Artery Stenosis, a 4D‐PCMRI Assessment

医学 颈内动脉 狭窄 心脏病学 脑血流 大脑中动脉 大脑前动脉 脑动脉 磁共振成像 内科学 磁共振血管造影 血流动力学 放射科 缺血
作者
Laleh Zarrinkoob,Sanne Myrnäs,Anders Wåhlin,Anders Eklund,Jan Malm
出处
期刊:Journal of Magnetic Resonance Imaging [Wiley]
被引量:4
标识
DOI:10.1002/jmri.29216
摘要

Background Compromised cerebral blood flow can contribute to future ischemic events in patients with symptomatic carotid artery disease. However, there is limited knowledge of the effects on cerebral hemodynamics resulting from a reduced internal carotid artery (ICA) blood flow rate (BFR). Purpose Investigate how reduced ICA‐BFR, relates to BFR in the cerebral arteries. Study Type Prospective. Subjects Thirty‐eight patients, age 72 ± 6 years (11 female). Field Strength/Sequence 3‐Tesla, four‐dimensional phase‐contrast magnetic resonance imaging (4D‐PCMRI). Assessment Patients with ischemic stroke or transient ischemic attack were evaluated regarding the degree of stenosis. 4D‐PCMRI was used to measure cerebral BFR in 38 patients with symptomatic carotid stenosis (≥50%). BFR in the cerebral arteries was assessed in two subgroups based on symptomatic ICA‐BFR: reduced ICA‐flow (<160 mL/minutes) and preserved ICA‐flow (≥160 mL/minutes). BFR laterality was defined as a difference in the paired ipsilateral‐contralateral arteries. Statistical Tests Patients were grouped based on ICA‐BFR (reduced vs. preserved). Statistical tests (independent sample t ‐test/paired t ‐test) were used to compare groups and hemispheres. Significance was determined at P < 0.05. Results The degree of stenosis was not significantly different, 80% (95% confidence interval [CI] = 73%–87%) in the reduced ICA‐flow vs. 72% (CI = 66%–76%) in the preserved ICA‐flow; P = 0.09. In the reduced ICA‐flow group, a significantly reduced BFR was found in the ipsilateral middle cerebral artery and anterior cerebral artery (A1), while significantly increased in the contralateral A1. Retrograde BFR was found in the posterior communicating artery and ophthalmic artery. Significant BFR laterality was present in all paired arteries in the reduced ICA‐flow group, contrasting the preserved ICA‐flow group ( P = 0.14–0.93). Data Conclusions 4D‐PCMRI revealed compromised cerebral BFR due to carotid stenosis, not possible to detect by solely analyzing the degree of stenosis. In patients with reduced ICA‐flow, collaterals were not sufficient to maintain symmetrical BFR distribution to the two hemispheres. Evidence Level 2 Technical Efficacy Stage 3
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
5High_0完成签到 ,获得积分10
4秒前
9秒前
陈苗发布了新的文献求助10
15秒前
uuuuu完成签到,获得积分10
15秒前
优美的谷完成签到,获得积分10
20秒前
Panini完成签到 ,获得积分10
24秒前
24秒前
老夫子发布了新的文献求助10
24秒前
喂喂发布了新的文献求助10
28秒前
orixero应助bksqc采纳,获得10
33秒前
wukong完成签到,获得积分10
36秒前
47秒前
51秒前
丁元英完成签到,获得积分10
52秒前
52秒前
56秒前
Aqib发布了新的文献求助10
59秒前
陈苗完成签到,获得积分20
1分钟前
果果发布了新的文献求助10
1分钟前
天天快乐应助董可以采纳,获得10
1分钟前
wanci应助Aqib采纳,获得10
1分钟前
怕孤独的孤萍完成签到 ,获得积分10
1分钟前
cheng完成签到 ,获得积分10
1分钟前
1分钟前
辉哥完成签到,获得积分10
1分钟前
1分钟前
LMY完成签到 ,获得积分10
1分钟前
1分钟前
PEITON发布了新的文献求助10
1分钟前
1分钟前
lenon发布了新的文献求助10
2分钟前
半夏完成签到 ,获得积分10
2分钟前
2分钟前
董可以发布了新的文献求助10
2分钟前
2分钟前
miracle完成签到 ,获得积分10
2分钟前
sss发布了新的文献求助10
2分钟前
华桦子完成签到 ,获得积分10
2分钟前
凌灵翎完成签到,获得积分10
2分钟前
lenon完成签到,获得积分10
2分钟前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3990022
求助须知:如何正确求助?哪些是违规求助? 3532092
关于积分的说明 11256327
捐赠科研通 3270943
什么是DOI,文献DOI怎么找? 1805140
邀请新用户注册赠送积分活动 882270
科研通“疑难数据库(出版商)”最低求助积分说明 809228