医学
荟萃分析
慢性静脉功能不全
类黄酮
内科学
水肿
外科
生物化学
抗氧化剂
化学
作者
Eberharde RABE,Vanessa Blanc‐Guillemaud,Marie-Blanche Onselaer,Yoann Blangero,Hurrem-Pelin YALTIRIK,Andrew Nicolaides
标识
DOI:10.23736/s0392-9590.23.05084-8
摘要
The prevalence of lower limb edema is high among patients with chronic venous disease (CVD). Several clinical studies with various designs have assessed the effect of micronized purified flavonoid fraction (MPFF) on edema. The aim of this work was to provide a comprehensive and accurate evaluation of the reduction in ankle and calf circumference as an indicator of lower limb edema reduction in patients with CVD treated with MPFF by combining studies that use different designs in a single group meta-analysis.
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