Cardiovascular Toxicity of Nanoparticles

The integration of nanotechnology into various industries has raised concerns about potential health risks, particularly regarding cardiovascular toxicity. This book chapter comprehensively examines the impact of nanoparticles on the cardiovascular system, elucidating the underlying mechanisms and critical factors influencing toxicity. It reviews the current state of research on nanoparticle exposure via different routes, such as inhalation and ingestion, and their subsequent distribution in the cardiovascular system. Furthermore, the chapter delves into the cellular and molecular events triggering adverse cardiovascular effects, including oxidative stress, inflammation, and endothelial dysfunction. Understanding these toxicological aspects is crucial in developing effective safety guidelines and tailored nanomedical interventions for safer nanotechnology applications.