Impact of high-resolution intracranial vessel wall magnetic resonance imaging on diagnosis in patients with embolic stroke of unknown source

医学 冲程(发动机) 优势比 磁共振成像 置信区间 心脏病学 风险因素 放射科 内科学 机械工程 工程类
作者
Naaem Simaan,Fatma Shalabi,Yoel Schwartzmann,Tamer Jubeh,Yoav Parag,Asaf Honig,Issa Metanis,Hamza Joubran,Jad Magadlla,John M. Gomori,José E. Cohen,Ronen R. Leker
出处
期刊:Journal of the Neurological Sciences [Elsevier BV]
卷期号:454: 120863-120863 被引量:2
标识
DOI:10.1016/j.jns.2023.120863
摘要

The mechanism responsible for stroke in patients with embolic stroke of unknown source (ESUS) often remains unknown despite extensive investigations. We aimed to test whether high-resolution intracranial vessel wall MR imaging (icVWI) can add to the diagnostic yield in these patients.Patients with ESUS were prospectively included into an ongoing registry. Patients that underwent icVWI as part of their diagnostic workup were compared to those that did not have an icVWI. Patients with icVWI positive for intracranial vulnerable plaques were than compared to those without evidence of plaque vulnerability on VWI.A total of 179 patients with ESUS were included and 48 of them (27%) underwent icVWI. Patients that had an icVWI scan were significantly younger, had lower rates of ischemic heart disease and prior disability as well as significantly lower stroke severity. On regression analysis the only factor that remained associated with not obtaining an icVWI scan was increasing age (Odds ratio [OR] 0.97/year, 95% confidence intervals [CI] 0.95-0.97). Among patients that had an icVWI scan 28 (58%) had evidence of plaque enhancement on VWI in the same distribution of the stroke and the remaining 20 studies were negative. The relative proportion of stroke presumed to be secondary to intracranial non-stenotic atheromatous disease increased from 15% in patients without icVWI scans to 58% among patients with icVWI scans (p = 0.001). On regression analysis the only factor that was associated with vulnerable plaques on icVWI was smoking (OR 11.05 95% CI 1.88-65.17).icVWI can add significant information relevant to stroke pathogenesis and treatment in patients with ESUS and a negative initial exhaustive diagnostic workup.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
YL完成签到,获得积分10
1秒前
NexusExplorer应助小王采纳,获得10
2秒前
2秒前
sl完成签到,获得积分10
2秒前
CC完成签到,获得积分10
3秒前
自信松思完成签到 ,获得积分10
4秒前
荣枫完成签到,获得积分10
4秒前
4秒前
火火火木完成签到 ,获得积分10
5秒前
大模型应助妖孽宇采纳,获得10
5秒前
7秒前
积极行天发布了新的文献求助50
7秒前
受伤凌蝶发布了新的文献求助10
10秒前
fusucheng完成签到,获得积分10
11秒前
koi完成签到,获得积分20
11秒前
11秒前
聪明摩托完成签到,获得积分10
11秒前
阿纯完成签到,获得积分10
12秒前
13秒前
肱二头肌完成签到,获得积分10
14秒前
15秒前
小王发布了新的文献求助10
15秒前
多情自古空余恨完成签到,获得积分10
16秒前
Qionglin完成签到,获得积分10
18秒前
Bao完成签到 ,获得积分10
19秒前
19秒前
初夏微凉发布了新的文献求助30
19秒前
20秒前
书霂完成签到,获得积分10
20秒前
优秀含羞草完成签到,获得积分10
21秒前
宓沂完成签到,获得积分10
21秒前
vivre223完成签到,获得积分10
21秒前
量子星尘发布了新的文献求助10
22秒前
受伤凌蝶完成签到,获得积分10
23秒前
wenjiejiang完成签到,获得积分10
24秒前
24秒前
zly完成签到 ,获得积分10
25秒前
25秒前
李某人完成签到,获得积分10
25秒前
26秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
Research on Disturbance Rejection Control Algorithm for Aerial Operation Robots 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038388
求助须知:如何正确求助?哪些是违规求助? 3576106
关于积分的说明 11374447
捐赠科研通 3305798
什么是DOI,文献DOI怎么找? 1819322
邀请新用户注册赠送积分活动 892672
科研通“疑难数据库(出版商)”最低求助积分说明 815029