Sex-related differences in psoriatic arthritis

Psoriatic arthritis is a complex musculoskeletal inflammatory disease characterised by the association of arthritis and psoriasis with extra-articular manifestations and several comorbid conditions. 1 Ritchlin CT Colbert RA Gladman DD Psoriatic arthritis. N Engl J Med. 2017; 376: 957-970 Crossref PubMed Scopus (769) Google Scholar , 2 Lubrano E Scriffignano S Perrotta FM Psoriatic arthritis, psoriatic disease, or psoriatic syndrome?. J Rheumatol. 2019; 46: 1428-1430 Crossref PubMed Scopus (32) Google Scholar Sex-related differences in patient characteristics, and efficacy and safety of advanced therapies in randomised clinical trials in psoriatic arthritis: a systematic literature review and meta-analysisBiological sex of patients with psoriatic arthritis influences their response to advanced therapies, but the effect varies by drug class. Selective reporting might have influenced these results. Future trials should report baseline characteristics and endpoint results by sex. Full-Text PDF