Nano techniques: an updated review focused on anthocyanin stability

AbstractAnthocyanins (ACNs) are one of the subgroups of flavonoids and getting intensive attraction due to the nutritional values. However, their application of ACNs is limited due to their poor stability and bioavailability. Accordingly, nanoencapsulation has been developed to enhance its stability and bio-efficacy. This review focuses on the nano-technique applications of delivery systems that be used for ACNs stabilization, with an emphasis on physicochemical stability and health benefits. ACNs incorporated with delivery systems in forms of nano-particles and fibrils can achieve advanced functions, such as improved stability, enhanced bioavailability, and controlled release. Also, the toxicological evaluation of nano delivery systems is summarized. Additionally, this review summarizes the challenges and suggests the further perspectives for the further application of ACNs delivery systems in food and medical fields.Keywords: Pigmentsnano-particlesnano-fibrilsstabilitybioavailability Author contributionsP.J. conceived the idea; T.S.L. constructed the manuscript; T.S.L., J.H. and P.J. edited and revised the whole manuscript; and the final version was approved by all authors.Disclosure statementThe authors declare that they have no competing interests.Additional informationFundingThe authors are grateful for the financial assistance from the National Natural Science Foundation of China (Grant No. 21978169) and the Key-Area Research and Development Program of Guangdong Province (Grant No. 2018B020239001).