Multi-Surface Cartilage Defects about the Knee Treated with Cartilage Restoration Procedures Show Good Outcomes and Survivorship at Minimum 2-Year Follow-Up

医学 自体软骨细胞移植 软骨 正式舞会 髌骨 外科 骨关节炎 最小临床重要差异 关节面 移植 关节置换术 关节软骨 替代医学 病理 产科 解剖 随机对照试验
作者
Julia Retzky,Guilherme Palhares,Morgan Rizy,Paige Hinkley,Andreas H. Gomoll,Sabrina Strickland
出处
期刊:Cartilage [SAGE]
被引量:1
标识
DOI:10.1177/19476035231207780
摘要

We aimed to evaluate the outcomes, survivorship, and complications following multi-surface cartilage procedures at minimum 2-year follow-up.Patients with either (1) single-surface osteochondral allograft transplantation (OCAT) with third-generation matrix-induced autologous cultured chondrocyte implantation (MACI) or particulated juvenile cartilage implantation (DeNovo), or (2) multiple-surface OCAT ± associated MACI/DeNovo procedures for grade IV chondral or osteochondral defects about the knee with minimum 2-year follow-up were analyzed. Patient-reported outcome measures (PROMs), including International Knee Documentation Committee (IKDC) and Knee Injury and Osteoarthritis Outcome Score (KOOS) subscales, were obtained preoperatively and at minimum 2 years postoperatively. The percentage of patients who met the minimal clinically important difference (MCID) for each PROM was reported. Failure was defined as revision OCAT, conversion to patellofemoral/total/unicompartmental joint arthroplasty, or Arthrosurface HemiCAP placement.Of 257 patients identified, 35 were included. There was a significant increase in IKDC, KOOS-pain, KOOS-symptom, KOOS-sport, and KOOS-quality of life scores from preoperative to postoperative evaluation (P < 0.03 for all). More than 50% of patients met the MCID for each PROM. There were 2 failures, 1 of the patella and 1 of the medial femoral condyle, at 39.7 and 38.6 months postoperatively, respectively.Multi-surface cartilage procedures are a safe, efficacious treatment option for multifocal cartilage defects about the knee at short-term follow-up.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
LC完成签到 ,获得积分10
刚刚
刚刚
失眠绝音完成签到 ,获得积分10
1秒前
雪白水池发布了新的文献求助10
1秒前
林七七发布了新的文献求助10
2秒前
上官若男应助风中成风采纳,获得10
2秒前
4秒前
4秒前
5秒前
lewong发布了新的文献求助10
6秒前
tuanheqi应助神宝宝采纳,获得30
7秒前
风中成风完成签到,获得积分10
7秒前
滴滴答答完成签到 ,获得积分10
8秒前
8秒前
9秒前
Melo关注了科研通微信公众号
9秒前
qiuqiu完成签到 ,获得积分10
9秒前
9秒前
10秒前
逢投必中发布了新的文献求助10
11秒前
qiao完成签到,获得积分10
11秒前
JIANYOUFU完成签到,获得积分10
11秒前
ycw123完成签到,获得积分10
12秒前
华仔应助老科研人采纳,获得50
12秒前
12秒前
jiangww发布了新的文献求助10
14秒前
aoba发布了新的文献求助10
14秒前
15秒前
穆思柔发布了新的文献求助10
16秒前
茶叶酱完成签到,获得积分10
16秒前
16秒前
16秒前
嗯哼完成签到 ,获得积分10
17秒前
17秒前
20秒前
HQK发布了新的文献求助10
20秒前
欣慰小蕊完成签到,获得积分10
21秒前
21秒前
22秒前
李浩然发布了新的文献求助10
23秒前
高分求助中
Spray / Wall-interaction Modelling by Dimensionless Data Analysis 2000
ALA生合成不全マウスでの糖代謝異常の分子機構解析 520
Mathematics and Finite Element Discretizations of Incompressible Navier—Stokes Flows 500
A new species of Coccus (Homoptera: Coccoidea) from Malawi 500
2-Acetyl-1-pyrroline: an important aroma component of cooked rice 500
A real-time energy management strategy based on fuzzy control and ECMS for PHEVs 400
Handbook on People's China (1957) 400
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3189389
求助须知:如何正确求助?哪些是违规求助? 2838764
关于积分的说明 8021434
捐赠科研通 2501634
什么是DOI,文献DOI怎么找? 1335889
科研通“疑难数据库(出版商)”最低求助积分说明 637729
邀请新用户注册赠送积分活动 605784