Down‐regulation of CYTL1 attenuates bleomycin‐induced pulmonary fibrosis in mice by inhibiting M2 macrophage polarization via the TGF‐β/CCN2 axis

Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by chronic inflammation, lung tissue fibrotic changes and impaired lung function. Pulmonary fibrosis 's pathological process is thought to be influenced by macrophage-associated phenotypes. IPF treatment requires specific targets that target macrophage polarization. Cytokine-like 1(CYTL1) is a secreted protein with multiple biological functions first discovered in CD34