生物
作用机理
机制(生物学)
基因
翻译(生物学)
计算生物学
功能(生物学)
基因表达
转移
转录活性
基因表达调控
生物信息学
遗传学
癌症研究
细胞生物学
信使核糖核酸
癌症
体外
哲学
认识论
作者
Yan Gao,Yanzhao Huang,Kaiyun Guo,Jun Cheng,Yuting Luo,Yi Deng,Lei Ming
标识
DOI:10.1136/jmg-2024-110437
摘要
tsRNA is a class of non-coding RNAs derived from mature or precursor tRNAs. In recent years, more and more studies have explored the correlation between tsRNAs and tumours. tsRNAs can affect the biological behaviours of tumour cells such as proliferation, apoptosis and metastasis by regulating gene expression, protein translation or post-transcriptional regulation. In this paper, we systematically review the production, biological function and research progress of tsRNA in tumour and discuss its prospects as biomarkers and therapeutic targets.
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