化学
环加成
串联
醌
原位
光化学
氢原子
电子转移
组合化学
立体化学
有机化学
催化作用
群(周期表)
材料科学
复合材料
作者
Wang Shu,Liang Ge,Cheng Wang,Chenhong Wang,Zhiyuan Huang,Chen‐Ho Tung,Li‐Zhu Wu
标识
DOI:10.1021/acs.orglett.4c04494
摘要
Reported herein is the generation of ortho-quinone methides (o-QMs) via metal-free visible-light-induced oxidation of ortho-alkylarenols, as well as their subsequent reaction with olefins to afford chromans in good to excellent yields (up to 91%). The key is the selective activation of the benzylic C(sp3)–H bond of ortho-alkylarenols via single electron transfer (SET) and the formation of o-QMs via hydrogen atom transfer (HAT).
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