Ulcerative Colitis Severity Classification and Localised Extent (UC-SCALE): An Artificial Intelligence scoring system for a spatial assessment of disease severity in Ulcerative Colitis

Validated scoring methods such as the Mayo Clinic Endoscopic Subscore (MCES) evaluate ulcerative colitis (UC) severity at the worst colon segment, without considering disease extent. We present the Ulcerative Colitis Severity Classification and Localised Extent (UC-SCALE) algorithm, which provides a comprehensive and automated evaluation of endoscopic severity and disease extent in UC.