Building the Future Management of Follicular Lymphoma with T-Cell-Redirecting Strategies
滤泡性淋巴瘤
医学
淋巴瘤
免疫学
作者
Gloria Iacoboni,Franck Morschhauser
出处
期刊:Blood [American Society of Hematology] 日期:2024-11-14
标识
DOI:10.1182/blood.2024025699
摘要
Follicular lymphoma (FL) usually requires multiple lines of therapy and disease control remains largely insufficient with conventional chemoimmunotherapy. Several T-cell redirecting strategies recently approved in the relapsed/refractory setting have the potential to improve outcomes and change the treatment algorithm in FL. This review focuses on the role of chimeric antigen receptor T-cells and bispecific antibodies in FL, paying special attention to sequencing approaches and future directions.