Maxillofacial bone defect can seriously affect the patient's appearance, mastication, deglutition and speech function. At present, autologous bone grafting combined with implant repair is an effective method for reconstruction of maxillofacial bone defects. Due to the differences in density, nutrition, immunity and other aspects of bone graft at different donor sites, there may be a potential impact on implant repair. In this paper, the biological characteristics of vascularized autologous bone used in maxillofacial bone defect repair were reviewed, and the risk factors of implantation on the bone graft were discussed. It provides support for clinicians in the selection of bone graft donor site and the design of prosthesis.颌骨缺损严重影响患者的外貌,并影响其咀嚼、吞咽和语言功能。自体骨移植伴种植修复是目前实现颌骨缺损修复重建的有效手段。不同供区来源的移植骨由于密度、营养、免疫等方面存在差异,可能影响种植修复的成功率。本文阐述了目前应用于颌面部骨缺损修复的血管化自体骨及其生物学特性,并探讨了移植骨种植修复的风险因素,以期为临床医师进行移植骨供区选择及修复方案设计提供参考。.