金黄色葡萄球菌
铜绿假单胞菌
抗生素
皮肤感染
免疫系统
致病菌
微生物学
医学
葡萄球菌皮肤感染
痤疮
抗生素耐药性
细菌
抗菌剂
免疫学
生物
皮肤病科
遗传学
作者
Swasti Rawal,Syed Azmal Ali
出处
期刊:Food & Function
[The Royal Society of Chemistry]
日期:2023-01-01
卷期号:14 (9): 3966-3981
被引量:15
摘要
Probiotics and postbiotics have emerged as an alternative to traditional antibiotics for the treatment of persistent skin infections. The use of probiotics and postbiotics has been shown to have a positive impact on the maintenance of skin health by promoting the growth of beneficial bacteria and inhibiting the growth of harmful bacteria. Probiotics work by adhering to the skin and mucosal membranes and competing with pathogenic organisms for nutrients, which prevent the growth of harmful bacteria. In addition, probiotics and postbiotics produce antimicrobial substances that help eliminate pathogenic bacteria, resulting in improved skin health. The skin is the largest organ in the body and serves as a protective barrier against external pathogens. When harmful bacteria colonize the skin, it can lead to tissue damage and disruption, which can cause chronic inflammatory, non-healing skin disorders such as dermatitis, psoriasis, and acne. Traditional treatments for persistent skin infections rely heavily on antibiotics, which can have several adverse effects on the body, including the development of antibiotic resistance. Moreover, pathogens such as Pseudomonas aeruginosa and Staphylococcus aureus, which are often implicated in chronic skin infections, can form biofilms that are highly resistant to antibiotics and host immune responses. In recent years, research has shown that probiotics and postbiotics can play a significant role in the maintenance of dermal health. Probiotics and postbiotics can stimulate the immune system, enhance the production of skin barrier components, and modulate skin inflammation, all of which are critical for the maintenance of healthy skin. In this review, we have compiled the current literature on the therapeutic potential of probiotics and postbiotics for the treatment of persistent skin infections and their impact on maintaining dermal health.
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