线索反应性
渴求
心理学
海洛因
眶额皮质
上瘾
前额叶腹内侧皮质
渴望食物
扣带回前部
背外侧前额叶皮质
伏隔核
前额叶皮质
神经科学
精神科
药品
认知
多巴胺
作者
Yuefeng Huang,Ahmet O. Ceceli,Greg Kronberg,Sarah G. King,Pias Malaker,Muhammad A. Parvaz,Nelly Alia‐Klein,Eric L. Garland,Rita Z. Goldstein
标识
DOI:10.1176/appi.ajp.20220759
摘要
The results demonstrate cortico-striatal upregulation during drug cue exposure and impaired reactivity during processing of alternative non-drug rewards in the heroin use disorder group. Normalizing cortico-striatal function by reducing drug cue reactivity and enhancing natural reward valuation may inform therapeutic mechanisms for reducing drug craving and seeking in heroin addiction.
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