Flexible, Electrospun Boron Nitride Nanosheets (BNNS)/Hydroxyapatite -PVDF Nanofibers with Superior Piezoelectric/Ferroelectric, Biocompatible Features for Effective Bone Tissue Regeneration

材料科学 氮化硼 生物相容性材料 纳米纤维 压电 静电纺丝 再生(生物学) 铁电性 骨组织 复合材料 纳米技术 生物医学工程 聚合物 电介质 细胞生物学 生物 医学 光电子学
作者
Anshida Mayeen,Anjana Santhosh,Noel Joseph,Jiya Jose,Abhirami Manoj,Saju Joseph,Sarita G. Bhat,Honey John
出处
期刊:Journal of Alloys and Compounds [Elsevier BV]
卷期号:: 175111-175111
标识
DOI:10.1016/j.jallcom.2024.175111
摘要

Piezoelectric/ferroelectric scaffolds are emerging tools in tissue engineering that offer new platforms for the repair and regeneration of damaged soft and hard tissues by means of electrical stimulation. In line with this, boron nitride nanosheets (BNNS)/hydroxyapatite (H)-polyvinylidene fluoride (PVDF) based piezoelectric electrospun nanofibers were developed for effective bone tissue regeneration. BNNS were prepared through a sequential process involving lithium intercalation, followed by hydrothermal exfoliation. Four distinct sets of nanofibers were prepared by altering the concentration of BNNS (2.5 wt.%, 5 wt.%, 10 wt.%) while maintaining a constant concentration of HAP nanoparticles which was prepared by sol-gel method (2.5 wt%) in the PVDF polymer matrix. The piezoelectric/ferroelectric performance of the PVDF-H-BNNS nanofibers were found to be enhanced with the addition of BNNS. The PVDF-H-BNNS nanofibers, with an effective contact area of 1 cm2, exhibited remarkable piezoelectric characteristics, exhibiting a peak voltage of 13 V and a current of 1.63 µA under the influence of 10 N force at a frequency of 10 Hz, showcasing their exceptional electromechanical response. The cytocompatibility studies of PVDF-H-BNNS nanofibers on MG-63 and HOS cell lines reveals excellent viability of nanofibers, akin to that control. Cell proliferation investigations conducted with MG-63 and HOS cell lines on PVDF-H-BNNS showcased the remarkable biocompatibility of the engineered membranes. The PVDF-H-BNNS piezoelectric nanofibers, having exceptional piezo-response and enhanced cytocompatibility, hold promise as ideal candidates for applications in the field of bone tissue engineering.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
CipherSage应助机灵的飞兰采纳,获得10
1秒前
潇洒的白凝完成签到,获得积分10
1秒前
2秒前
33完成签到,获得积分10
4秒前
夕拾发布了新的文献求助10
6秒前
Owen应助聪慧小霜采纳,获得10
7秒前
Hello应助聪慧小霜采纳,获得10
7秒前
思源应助聪慧小霜采纳,获得10
7秒前
所所应助聪慧小霜采纳,获得10
7秒前
Lucas应助聪慧小霜采纳,获得10
7秒前
言亦云应助聪慧小霜采纳,获得30
7秒前
8秒前
所所应助yuyu采纳,获得10
10秒前
云海老完成签到,获得积分10
11秒前
jimskylxk完成签到,获得积分10
11秒前
Joker完成签到,获得积分20
11秒前
研友_VZG7GZ应助聪慧小霜采纳,获得10
12秒前
ding应助聪慧小霜采纳,获得10
13秒前
情怀应助聪慧小霜采纳,获得30
13秒前
可爱的函函应助聪慧小霜采纳,获得10
13秒前
13秒前
酷波er应助聪慧小霜采纳,获得10
13秒前
无花果应助聪慧小霜采纳,获得30
13秒前
丘比特应助聪慧小霜采纳,获得10
13秒前
乐乐应助聪慧小霜采纳,获得10
13秒前
善学以致用应助聪慧小霜采纳,获得10
13秒前
Jasper应助聪慧小霜采纳,获得30
13秒前
U2完成签到,获得积分10
14秒前
14秒前
smottom应助puzhongjiMiQ采纳,获得10
15秒前
天天快乐应助puzhongjiMiQ采纳,获得10
15秒前
王鹏飞应助puzhongjiMiQ采纳,获得10
15秒前
JamesPei应助puzhongjiMiQ采纳,获得10
15秒前
万能图书馆应助puzhongjiMiQ采纳,获得10
15秒前
王鹏飞应助puzhongjiMiQ采纳,获得10
15秒前
王鹏飞应助puzhongjiMiQ采纳,获得10
15秒前
张童鞋完成签到 ,获得积分10
16秒前
16秒前
Albertxkcj发布了新的文献求助10
18秒前
Jero完成签到 ,获得积分10
18秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3969557
求助须知:如何正确求助?哪些是违规求助? 3514377
关于积分的说明 11173836
捐赠科研通 3249692
什么是DOI,文献DOI怎么找? 1794979
邀请新用户注册赠送积分活动 875537
科研通“疑难数据库(出版商)”最低求助积分说明 804836