氢胺化
化学
胺气处理
芳基
烯烃纤维
组合化学
有机化学
卤代芳基
胺化
催化作用
烷基
作者
Jinghan Gui,Chung-Mao Pan,Ying Jin,Tian Qin,Julian C. Lo,Bryan J. Lee,Steven H. Spergel,Michael Mertzman,William J. Pitts,Thomas E. La Cruz,Michael A. Schmidt,Nitin B. Darvatkar,S. Natarajan,Phil S. Baran
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2015-05-22
卷期号:348 (6237): 886-891
被引量:431
标识
DOI:10.1126/science.aab0245
摘要
Stitching C-N bonds from nitro groups Numerous compounds in pharmaceutical research have carbon-nitrogen bonds, and chemists are always looking for ways to make them more efficiently. Gui et al. present a method that links the carbon in an olefin to the nitrogen in a nitroaromatic compound (see the Perspective by Kürti). Nitroaromatics are readily available, and the method tolerates a wide range of other chemical groups present on either reacting partner. Science , this issue p. 886 ; see also p. 863
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