TBAF‐Catalyzed Tandem Synthesis of Triazolo[4,5‐c]quinolines at Ambient Temperature

A mild, efficient and metal‐free synthetic method for 1 H ‐[1,2,3]triazolo[4,5‐ c ]quinolines has been developed via intermolecular [3+2] cycloaddition of β‐(2‐aminoaryl)‐α,β‐ynones and TMS‐N 3 , followed by intramolecular dehydration annulation sequential reactions. With 5 mmol‐% of TBAF as catalyst, the reaction can smoothly proceed in DMF at ambient temperature to afford a wide range of functionalized 1 H ‐[1,2,3]triazolo[4,5‐ c ]quinolines in good to excellent yields.