亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Relationship Between Recreational Marijuana Use and Bowel Function in a Nationwide Cohort Study

医学 便秘 优势比 腹泻 队列 内科学 体质指数 全国健康与营养检查调查 队列研究 大麻 环境卫生 人口 精神科
作者
Adeyinka Adejumo,Ryan Flanagan,Braden Kuo,Kyle Staller
出处
期刊:The American Journal of Gastroenterology [Lippincott Williams & Wilkins]
卷期号:114 (12): 1894-1903 被引量:19
标识
DOI:10.14309/ajg.0000000000000441
摘要

OBJECTIVES: Although the endogenous cannabinoid system modulates bowel function, our understanding of the impact of recreational marijuana (MJ) use on bowel motility is limited. This study examines the effect of MJ on self-reported bowel function among a large cohort of US adults. METHODS: We identified adults (age: 20–59 years) who completed both the drug use and bowel health questionnaires in the National Health and Nutrition Examination Survey over a 6-year period from 2005 to 2010 (n = 9,645). Constipation and diarrhea were defined according to stool form (Bristol Stool Form Scale) and/or frequency criteria. Adjusted odds ratios (AORs) for likelihood of constipation or diarrhea were estimated in a multinomial logistic model according to MJ use status. RESULTS: Overall, constipation prevalence was lower among those with recent MJ use compared with those with past/never use (7.5% vs 10.2%, P = 0.03). Recent MJ use was associated with a 30% decreased odds of constipation (crude odds ratio: 0.71 [0.56–0.98], P = 0.005), which persisted after stepwise adjustment for age and other demographic factors including sex, ethnicity, education, body mass index, and socioeconomic status (AOR: 0.64 [0.49–0.83], P = 0.001); comorbidities, substance use (alcohol, tobacco, heroin, and cocaine), constipating medications, general health condition, rigorous physical activity, and emotional disturbances (AOR: 0.68 [0.48–0.93], P = 0.016); and diet (AOR: 0.68 [0.52–0.89], P = 0.006). There was no association between recent MJ use and diarrhea. DISCUSSION: In a nationally representative sample of community-dwelling US adults, recent MJ use was associated with decreased odds of constipation, counter to the known physiologic effects of cannabinoids on colonic motility.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
林子青完成签到,获得积分10
14秒前
核桃发布了新的文献求助30
23秒前
李健应助reerwt采纳,获得10
31秒前
32秒前
ICSSCI发布了新的文献求助10
37秒前
40秒前
刘宇童给刘宇童的求助进行了留言
42秒前
reerwt发布了新的文献求助10
46秒前
48秒前
科研通AI2S应助科研通管家采纳,获得10
1分钟前
科研通AI2S应助科研通管家采纳,获得10
1分钟前
ICSSCI完成签到,获得积分10
1分钟前
1分钟前
董可以发布了新的文献求助10
1分钟前
风华正茂完成签到,获得积分10
2分钟前
2分钟前
2分钟前
jimmy_bytheway完成签到,获得积分0
2分钟前
桃桃发布了新的文献求助10
2分钟前
可爱的函函应助桃桃采纳,获得10
2分钟前
2分钟前
2分钟前
2分钟前
3分钟前
NexusExplorer应助科研通管家采纳,获得10
3分钟前
所所应助爱笑的毛衣采纳,获得10
3分钟前
3分钟前
3分钟前
duan完成签到 ,获得积分10
3分钟前
holder完成签到,获得积分10
4分钟前
4分钟前
沐白发布了新的文献求助10
4分钟前
4分钟前
刘宇童发布了新的文献求助10
4分钟前
大模型应助吕易巧采纳,获得10
4分钟前
迷人问兰完成签到,获得积分10
4分钟前
闪闪映易完成签到 ,获得积分10
4分钟前
4分钟前
吕易巧发布了新的文献求助10
4分钟前
吕易巧完成签到,获得积分10
4分钟前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3990049
求助须知:如何正确求助?哪些是违规求助? 3532108
关于积分的说明 11256354
捐赠科研通 3270976
什么是DOI,文献DOI怎么找? 1805166
邀请新用户注册赠送积分活动 882270
科研通“疑难数据库(出版商)”最低求助积分说明 809228