医学
蛛网膜下腔出血
剪裁(形态学)
自然史
神经影像学
并发症
动脉瘤
外科
血管内治疗
放射科
血管内卷取
内科学
语言学
精神科
哲学
作者
Yuval Elkun,Jared Cooper,Haris Kamal,Katarina Dakay,Halla Nuoaman,Yasir Adnan,Vincent Dodson,Rolla Nuoman,Kavneet Kaur,Christeena Kurian,Ramandeep Sahni,Chirag D. Gandhi,Fawaz Al‐Mufti
出处
期刊:Cardiology in Review
[Ovid Technologies (Wolters Kluwer)]
日期:2020-12-03
卷期号:29 (1): 33-38
被引量:4
标识
DOI:10.1097/crd.0000000000000333
摘要
Unruptured intracranial aneurysms measuring <7 mm in diameter have become increasingly prevalent due to advances in diagnostic imaging. The most feared complication is aneurysm rupture leading to a subarachnoid hemorrhage. Based on the current literature, the 3 main treatments for an unruptured intracranial aneurysm are conservative management with follow-up imaging, endovascular coiling, or surgical clipping. However, there remains no consensus on the best treatment approach. The natural history of the aneurysm and risk factors for aneurysm rupture must be considered to individualize treatment. Models including population, hypertension, age, size of aneurysm, earlier subarachnoid hemorrhage from a prior aneurysm, site of aneurysm score, Unruptured Intracranial Aneurysm Treatment Score, and advanced neuroimaging can assist physicians in assessing the risk of aneurysm rupture. Macrophages and other inflammatory modulators have been elucidated as playing a role in intracranial aneurysm progression and eventual rupture. Further studies need to be conducted to explore the effects of therapeutic drugs targeting inflammatory modulators.
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