表观遗传学
免疫系统
免疫学
免疫
效应器
医学
接种疫苗
剑
生物
遗传学
基因
计算机科学
操作系统
作者
Andrew R. DiNardo,Mihai G. Netea,Daniel M. Musher
标识
DOI:10.1056/nejmra2028358
摘要
Antigen-nonspecific host defenses are altered by infections, with epigenetic changes in the effector cells of natural immunity. Some of these changes enhance immune responses, and some interfere with them. The success of certain vaccination approaches may depend on finding a way to reverse the detrimental epigenetic effects of previous infection.
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