Engineered bacteria for bioremediation

The content gives a brief idea of various bioremediation strategies by genetically engineered bacteria. The use of engineered bacteria for remediation of xenobiotic/recalcitrant compounds is more feasible as compared to the physicochemical methods for remediation. Different biotechnological approaches like metabolic engineering, recombinant DNA technology, and omics approach are used for designing an efficient bioremediation strategy. Metabolic engineering of microbial regulatory pathways can offer the best way for increasing the ability of the microorganism to remediate bulk/large volume waste. Recombinant DNA technologies like construction of novel expression vectors, modification of gene regulatory networks, and methods to report the genetically modified organisms can serve as novel systems for bioremediation. Combination of metabolic engineering, rDNA technology, and omics has the potential to become an important tool, especially for the onsite bioremediation strategy.