Glucose‐dependent dielectric Cole‐Cole models of rat blood plasma from 500 MHz to 40 GHz for millimeter‐wave glucose detection

电介质 电导率 介电常数 相对介电常数 等离子体 粒子群优化 材料科学 分析化学(期刊) 极高频率 化学 生物系统 物理 数学 计算机科学 算法 电信 光电子学 色谱法 生物 量子力学 物理化学
作者
Marguerite T. Hays,Sydney Wojcieszak,Nikhat Nusrat,Lynn E. Secondo,Erdem Topsakal
出处
期刊:Microwave and Optical Technology Letters [Wiley]
卷期号:62 (9): 2813-2820 被引量:5
标识
DOI:10.1002/mop.32371
摘要

Abstract In 2017, 30.3 million Americans lived with diabetes. Currently, the standard method of glucose estimation for diabetes relies on electrochemical sensors which have limited lifespans and are only reliable continuously up to 400 mg/dL. This paper investigates an alternative sensing method using dielectric property variability as a function of glucose concentration. In this study, we characterize dielectric properties—relative permittivity and conductivity—of Sprague Dawley rat blood plasma as they relate to plasma glucose concentrations from 250 to 16 000 mg/dL, over an expanded frequency range of 500 MHz to 40 GHz with a 9.897 MHz resolution. Particle swarm optimization is then used to fit measured data to a single‐pole Cole‐Cole model for relative permittivity and conductivity. Quadratic relationships are developed to represent Cole‐Cole parameters as functions of glucose concentration. Accuracy of the Cole‐Cole model is determined by finding the difference between experimental data and Cole‐Cole approximations. Results suggest three main conclusions which may be applied to future sensing applications and testing: the single‐pole Cole‐Cole model is a reliable method to accurately describe and reconstitute dielectric properties according rat blood plasma glucose concentrations, conductivity is a more promising determinant of glucose concentration than relative permittivity, and higher frequency ranges result in larger conductivity contrast between glucose concentrations.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
zhoujianfuzhou完成签到,获得积分10
刚刚
2秒前
2秒前
3秒前
zhongjiaweiv发布了新的文献求助10
3秒前
666666发布了新的文献求助10
4秒前
Liu应助11122采纳,获得10
4秒前
共享精神应助11122采纳,获得10
4秒前
南兮发布了新的文献求助10
5秒前
5秒前
坚果发布了新的文献求助10
6秒前
白白发布了新的文献求助10
7秒前
云朵完成签到 ,获得积分10
7秒前
7秒前
water应助受伤幻桃采纳,获得10
8秒前
8秒前
king完成签到,获得积分20
9秒前
aku30完成签到,获得积分10
9秒前
吴高凤发布了新的文献求助10
10秒前
12秒前
14秒前
上官若男应助666666采纳,获得10
14秒前
juan完成签到,获得积分10
14秒前
无名发布了新的文献求助10
14秒前
余柳完成签到,获得积分10
15秒前
16秒前
17秒前
南兮完成签到,获得积分10
17秒前
18秒前
LIUC完成签到,获得积分20
18秒前
DW发布了新的文献求助10
20秒前
量子星尘发布了新的文献求助10
21秒前
22秒前
22秒前
深情安青应助XLL小绿绿采纳,获得10
22秒前
自由的忆文完成签到,获得积分10
22秒前
孔孔发布了新的文献求助50
23秒前
慕斯完成签到,获得积分10
24秒前
24秒前
27秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3971670
求助须知:如何正确求助?哪些是违规求助? 3516348
关于积分的说明 11182142
捐赠科研通 3251567
什么是DOI,文献DOI怎么找? 1795907
邀请新用户注册赠送积分活动 876155
科研通“疑难数据库(出版商)”最低求助积分说明 805318