Management of Chronic Nonbacterial Prostatitis/Chronic Pelvic Pain Syndrome

医学 多沙唑嗪 前列腺炎 盆腔疼痛 内科学 环丙沙星 慢性前列腺炎/慢性盆腔疼痛综合征 物理疗法 B组 前列腺 外科 抗生素 癌症 血压 微生物学 生物
作者
Benjamin Kulovac,Damir Aganović,Alden Prcić,Osman Hadžiosmanović
出处
期刊:Bosnian Journal of Basic Medical Sciences [Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina]
卷期号:7 (3): 245-249 被引量:14
标识
DOI:10.17305/bjbms.2007.3053
摘要

Chronic nonbacterial prostatitis/chronic pelvic pain syndrome is unsatisfactorily defined and insufficiently studied illness. Also, the treatment success is questionable and therefore, this illness is a therapeutical problem for urologists--which medications are the best choice in treating this uncomfortable condition? This paper presents results of prospective, open, analytical, comparative study that was performed on 90 patients with diagnosed chronic nonbacterial prostatitis/chronic pelvic pain syndrome. Patients were divided into three groups and were treated with two medications ciprofloxacin (C), doxazosin (D) and combination of ciprofloxacin + doxazosin (C+D). The effects were measured using symptom questionnaire for prostate illnesses of the National Institute for Health - USA (NIH-CPSI). During the basic evaluation, sum ranging from 0 to 43 was calculated for each patient. This number is called total sum NIH-CPSI (National Institutes of Health Chronic Prostatitis Symptom Index) of the questionnaire, which generates the questions from 1 to 9. The most significant change occurred in C+D group where the total sum changed from 18-38 in the beginning to 5-31 at the end of the treatment (55,1% (p<0,001)). Significant changes were also found in D group where the change was 46, 4% (p<0,001). At the end of the treatment no significant change was registered in C group (p<0,005): p<0,001--significance threshold. Combination of ciprofloxacin + doxazosin proved to be the best choice for treatment.

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