Gennady Ananchenko,Jasmina Novakovic,Johnathan Lewis
出处
期刊:Profiles of Drug Substances, Excipients and Related Methodology日期:2012-01-01卷期号:: 31-77被引量:14
标识
DOI:10.1016/b978-0-12-397220-0.00002-7
摘要
A review on physical and chemical properties, methods of preparation and analysis, as well as pharmacodynamics and pharmacokinetics of amlodipine besylate (3-ethyl 5-methyl (4RS)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate), an approved oral calcium channel blocker indicated for the treatment of angina pectoris and hypertension.