呼出气冷凝液
气体分析呼吸
医学
呼吸试验
生物标志物
重症监护医学
内科学
哮喘
化学
生物化学
解剖
幽门螺杆菌
作者
Michael D. Davis,Stephen J. Fowler,Alison Montpetit
标识
DOI:10.1016/j.prrv.2018.05.002
摘要
Exhaled breath is a robust matrix of biomarkers divided between three fractions – gaseous breath, volatile breath, and breath condensate. Breath is collected non-invasively through bags (for gaseous breath), cold condensation chambers (breath condensate), and adsorbent traps (volatile breath). Due to the incredibly dilute nature of breath matrices, breath biomarker analysis requires precise analytical techniques, highly sensitive technology and often challenges the limit of detection of even the most advanced assays. Interest and advances in breath collection, analysis, and use have increased in recent years largely due to advances in analytical technology. Approved and validated breath tests are available as tools for researchers and clinicians. Novel development is ongoing. This article reviews the current applications for exhaled breath biomarkers.
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