Prevalence of gestational diabetes and subsequent Type 2 diabetes among U.S. women

医学 妊娠期糖尿病 糖尿病 家族史 肥胖 逻辑回归 2型糖尿病 产科 怀孕 全国健康与营养检查调查 人口学 内科学 内分泌学 妊娠期 人口 环境卫生 社会学 生物 遗传学
作者
Sarah Stark Casagrande,Barbara Linder,Catherine C. Cowie
出处
期刊:Diabetes Research and Clinical Practice [Elsevier]
卷期号:141: 200-208 被引量:197
标识
DOI:10.1016/j.diabres.2018.05.010
摘要

Aims The true prevalence of gestational diabetes (GDM) in the United States is unknown. This study determined the prevalence of GDM and a subsequent diagnosis of diabetes in a nationally representative sample of U.S. women. Methods The crude and age-adjusted prevalence of GDM and subsequent diabetes were evaluated by sociodemographic and health-related characteristics among women age ≥20 years in the National Health and Nutrition Examination Surveys, 2007–2014 (N = 8185). Logistic regression analyzed independent factors associated with GDM and subsequent diabetes. Results The prevalence of GDM was 7.6%. Women who were Mexican American (vs. non-Hispanic white), had ≥4 live births (vs. 1), had a family history of diabetes, or were obese (vs. normal weight) had a higher age-standardized prevalence of GDM (each p < 0.04). Among women with a history of GDM, 19.7% had a subsequent diagnosis of diabetes; subsequent diabetes diagnosis was higher for those with health insurance, more time since GDM diagnosis, greater parity, family history of diabetes, and obesity, and lower for those with higher education and income (all p ≤ 0.005). By logistic regression, significant factors associated with GDM were age at first birth, parity, family history of diabetes, and obesity; significant factors for subsequent diabetes were older age, greater years since GDM diagnosis, less education, family history of diabetes, and obesity (each p < 0.01). Conclusions The prevalence of GDM in the U.S. was 7.6%, with 19.7% of these women having a subsequent diabetes diagnosis. Women with a history of GDM, family history of diabetes, and obesity should be carefully monitored for dysglycemia.
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