The Effect of High-Altitude Acclimatisation on Ultra-Short Heart Rate Variability

心率变异性 医学 心脏病学 心率 内科学 脉搏血氧仪 高海拔对人类的影响 血压 麻醉 解剖
作者
Christopher John Boos,Adrian Mellor,David Richard Woods,John Paul O’Hara
出处
期刊:Frontiers in Cardiovascular Medicine [Frontiers Media]
卷期号:9
标识
DOI:10.3389/fcvm.2022.787147
摘要

High-altitude (HA) exposure affects heart rate variability (HRV) and has been inconsistently linked to acute mountain sickness (AMS). The influence of increasing HA exposure on ultra-short HRV and its relationship to gold standard HRV measures at HA has not been examined.This was a prospective observational study of adults aged ≥ 18 years undertaking a HA trek in the Dhaulagiri region of the Himalayas. Cardiac inter-beat-intervals were obtained from a 10-s recording of supra-systolic blood pressure (Uscom BP+ device) immediately followed by 300 s single lead ECG recording (CheckMyHeart device). HRV was measured using the RMSSD (root mean square of successive differences of NN intervals) at sea level (SL) in the United Kingdom and at 3,619, 4,600, and 5,140 m at HA. Oxygen saturations (SpO2) were measured using finger-based pulse oximetry. The level of agreement between the 10 and 300 s RMSSD values were examined using a modified Bland-Altman relative-difference analysis.Overall, 89 participants aged 32.2 ± 8.8 years (range 18-56) were included of which 70.8% were men. HA exposure (SL vs. 3,619 m) was associated with an initial increase in both 10 s (45.0 [31.0-82.0]) vs. 58.0 [33.0-119.0] ms) and 300 s (45.67 [33.24-70.32] vs. 56.48 [36.98-102.0] ms) in RMSSD. Thereafter at 4,600 and 5,140 m both 10 and 300 s RMSSD values were significantly lower than SL. From a total of 317 paired HRV measures the 10 and 300 s RMSSD measures were moderately correlated (Spearman r = 0.66; 95% CI: 0.59-0.72; p < 0.0001). The median difference (bias) in RMSSD values (300 s - 10 s) was -2.3 ms with a lower and upper limit of agreement of -107.5 and 88.61 ms, respectively with no differences with altitude. Overall, 293/317 (92.4%) of all paired HRV values fell within the 95% CI limits of agreement. Neither HRV method was predictive of AMS.Increasing HA affects ultra-short HRV in a similar manner to gold-standard 300 s. Ultra-short HRV has a moderate agreement with 300 s measurements. HRV did not predict AMS.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1111111111111发布了新的文献求助10
刚刚
刚刚
科研通AI2S应助王冉冉采纳,获得10
刚刚
Xiaohu完成签到,获得积分10
1秒前
dtf完成签到,获得积分10
1秒前
凡迪亚比完成签到,获得积分10
1秒前
1秒前
香蕉觅云应助小朱佩奇采纳,获得10
2秒前
无语的代真完成签到,获得积分10
2秒前
3秒前
包凡之完成签到,获得积分10
4秒前
情怀应助自由橘子采纳,获得10
4秒前
zzz发布了新的文献求助10
4秒前
CipherSage应助1111111111111采纳,获得10
5秒前
搞怪南风完成签到,获得积分10
5秒前
文章使我快了完成签到,获得积分10
5秒前
cooper完成签到 ,获得积分10
6秒前
Ou发布了新的文献求助10
6秒前
sxx完成签到,获得积分10
6秒前
上官若男应助tanglu采纳,获得10
6秒前
麋鹿完成签到 ,获得积分10
6秒前
公西翠萱完成签到 ,获得积分10
6秒前
qixiaoqi发布了新的文献求助10
7秒前
博慧完成签到 ,获得积分10
8秒前
小刘医生完成签到,获得积分10
10秒前
安安完成签到,获得积分10
10秒前
啊啊啊啊完成签到,获得积分10
10秒前
英俊的铭应助飞飞鱼采纳,获得10
12秒前
科目三应助zzz采纳,获得10
12秒前
小小西瓜萝卜青菜完成签到,获得积分10
12秒前
思源应助虚幻采枫采纳,获得10
13秒前
13秒前
不安的可乐完成签到,获得积分10
13秒前
14秒前
nano完成签到 ,获得积分10
14秒前
da完成签到,获得积分10
14秒前
科研通AI2S应助啊啊啊啊采纳,获得10
15秒前
cyndi发布了新的文献求助20
15秒前
16秒前
852应助小小西瓜萝卜青菜采纳,获得10
18秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds第二卷 1200
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038657
求助须知:如何正确求助?哪些是违规求助? 3576306
关于积分的说明 11375198
捐赠科研通 3306108
什么是DOI,文献DOI怎么找? 1819379
邀请新用户注册赠送积分活动 892698
科研通“疑难数据库(出版商)”最低求助积分说明 815066